3-Trifluoromethoxyphenylboronic acid Basic information
Product Name: | 3-Trifluoromethoxyphenylboronic acid |
Synonyms: | AKOS BRN-0169;3-(TRIFLUOROMETHOXY)PHENYLBORONIC ACID;3-(TRIFLUOROMETHOXY)BENZENEBORONIC ACID;RARECHEM AH PB 0067;M-(TRIFLUOROMETHOXY)PHENYLBORONIC ACID;3-(Trifluoromethoxy)phenylboronic aicd;4-3-(TRIFLUOROMETHOXY)PHENYLBORONIC ACIDACID;3-(Trifluoromethoxy)Phenylboro |
CAS: | 179113-90-7 |
MF: | C7H6BF3O3 |
MW: | 205.93 |
EINECS: | -0 |
Product Categories: | blocks;BoronicAcids;FluoroCompounds;Boronic Acid series;Substituted Boronic Acids;Aryl;Boronic acid;Organoborons;B (Classes of Boron Compounds);Boronic Acids;CHIRAL CHEMICALS;Boronic Acids;Boronic Acids and Derivatives;Boronate Ester;Potassium Trifluoroborate |
Mol File: | 179113-90-7.mol |
| |
3-Trifluoromethoxyphenylboronic acid Chemical Properties
form | Powder and Chunks |
color | Almost white to slightly beige |
Appearance: | almost white to slightly beige powder and chunk |
Melting Point: | 84-89ºC |
Refractive Index: | 1.461 |
Storage Condition: | 0-6ºC |
Vapor Pressure: | 0.00425mmHg at 25°C |
BRN | 7531456 |
CAS DataBase Reference | 179113-90-7(CAS DataBase Reference) |
Safety Information
Hazard Codes | Xi,Xn |
Risk Statements | 36/37/38-20/21/22 |
Safety Statements | 37/39-26-36 |
WGK Germany | 3 |
Hazard Note | Irritant |
HS Code | 29163990 |
3-Trifluoromethoxyphenylboronic acid Usage And Synthesis
Chemical Properties | almost white to slightly beige powder and chunk |
Description | 3-(Trifluoromethyloxy)phenylboronic Acid is used as a reagent in the preparation of pyrrolo[1,2-a]pyrazinones as inhibitors of PIM kinases |
Uses | suzuki reaction |
Intermediate as | 1025065-69-3 SGI-1776
|
Synthesis route |
Reference:Leermann, Timo; Leroux, Frederic R.; Colobert, Francoise Organic Letters, 2011 , vol. 13, # 17 p. 4479 - 4481 |
3-Trifluoromethoxyphenylboronic acid Preparation Products And Raw materials
Upstream information
3-(Trifluoromethoxy)bromobenzene; [3-(trifluoromethoxy)phenyl]boronic acid; 4-Bromobenzaldehyde; 5-bromofuran-2-carbaldehyde;
Downtream information
3-(trifluoromethoxy)benzenesulfonyl chloride; 4-[3-(trifluoromethoxy)phenyl]benzaldehyde; 5-[3-(trifluoromethoxy)phenyl]furan-2-carbaldehyde; 1-[3-(trifluoromethoxy)phenyl]piperazine; [3-(trifluoromethoxy)phenyl]boronic acid
