3-Methoxycarbonylphenylboronic acid Basic information
Product Name: | 3-Methoxycarbonylphenylboronic acid |
Synonyms: | METHYL 3-BORONOBENZOATE;3-METHOXYCARBONYLPHENYLBORONIC ACID;3-(METHOXYCARBONYL)BENZENEBORONIC ACID;AKOS BRN-0125;M-(METHOXYCARBONYL)PHENYLBORONIC ACID;3-METHOXYCARBONYLPHENYLBARONIC ACID;3-(Methoxycarbonyl)phenylboronic Acid (contains varying amounts of Anhydride);3-Methoxycarbonylphenylboronic acid,97% |
CAS: | 99769-19-4 |
MF: | C8H9BO4 |
MW: | 179.97 |
EINECS: | |
Product Categories: | blocks;BoronicAcids;Carboxes;Acids and Derivatives;Boron, Nitrile, Thio,& TM-Cpds;Boronic acids;Aryl;Ester;Organoborons;B (Classes of Boron Compounds);Boronic acid;CHIRAL CHEMICALS;Aromatics;Boron Derivatives;Intermediates & Fine Chemicals;Pharmaceuticals;Boronate Ester;Potassium Trifluoroborate |
Mol File: | 99769-19-4.mol |
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3-Methoxycarbonylphenylboronic acid Chemical Properties
form | Powder |
color | White to off-white |
Appearance: | White to light yellow crystal powder |
Density: | 1.25g/cm3 |
Melting Point: | 187-191ºC |
Boiling Point: | 359.9ºC at 760 mmHg |
Flash Point: | 171.5ºC |
Refractive Index: | 1.532 |
Storage Condition: | Refrigerator (+4ºC) |
Water Solubility | Reacts with water. |
CAS DataBase Reference | 99769-19-4(CAS DataBase Reference) |
Safety Information
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 37/39-26-36 |
WGK Germany | 3 |
Hazard Note | Irritant |
HazardClass | IRRITANT |
Hs code | 2931900090 |
3-Methoxycarbonylphenylboronic acid Usage And Synthesis
Chemical Properties | White to light yellow crystal powde |
Uses | Used in the preparation of substituted pyrazolylpyrimidinamine derivative for use as protein kinase inhibitors. |
Uses | suzuki reaction |
Intermediate as | |
Synthesis route |
Reference:Wang, Xiao-Jun; Sun, Xiufeng; Zhang, Li; Xu, Yibo; Krishnamurthy, Dhileepkumar; Senanayake, Chris H. Organic Letters, 2006 , vol. 8, # 2 p. 305 - 307
Reference:Journal of the American Chemical Society, vol. 134, # 28 p. 11667 - 11673
Reference:Organic Letters, vol. 14, # 18 p. 4814 - 4817,4 |
3-Methoxycarbonylphenylboronic acid Preparation Products And Raw materials
Raw materials | Tetrahydrofuran-->Magnesium-->Triisopropyl borate-->Bis(2-dimethylaminoethyl) ether-->Methyl 3-iodobenzoate |
Upstream information
4-Bromobenzaldehyde; 3-Iodobenzoic acid; 2-bromopyridine; 2,3-dimethylbutane-2,3-diol; methanol; 1-Iodo-4-nitrobenzene; 3-Methoxycarbonylphenylboronic acid; Methyl 3-bromobenzoate; 4-Bromo-2-nitrophenol; zinc,dicyanide;
Downtream information
methyl 3-azidobenzoate; Methyl 4'-nitro-[1,1'-biphenyl]-3-carboxylate; 3-(4-hydroxy-3-nitrophenyl)benzoic acid; methyl 3-(3-methoxycarbonylphenyl)benzoate; Methyl 3-(trifluoromethyl)benzoate; Methyl 3-Fluorobenzoate; methyl 3-(4-formylphenyl)benzoate; Methyl 3-Cyanobenzoate; 3-Methoxycarbonylphenylboronic acid; 5-(3-methoxycarbonylphenyl)furan-2-carboxylic acid
