52488-36-5 4-Bromo-indole

52488-36-5 4-Bromo-indole

4-Bromoindole Basic information 4-Bromoindole Chemical Properties Safety Information MSDS Information 4-Bromoindole Usage And Synthesis 4-Bromoindole Preparation Products And Raw materials Upstream information 4-bromo-1-pivaloylindole; Phosphonium, [(2-bromo-6-nitrophenyl) methyl]triphenyl-,...
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Product Details

4-Bromoindole Basic information

Product Name:

4-Bromoindole

Synonyms:

4-BROMO-1H-INDOLE, 4-BROMOINDOLE; 4-BROMO-1H-INDAZOLE; 4-BROMO-INDOLE pure; 4-Bromoindole , 95%; 4-Bromo-1H-indole , TECH; 1H-Indole, 4-broMo-; 4-Bromoindole 96%; 4-BROMOINDOLE

CAS:

52488-36-5

MF:

C8H6BrN

MW:

196.04

EINECS:

-0

Product Categories:

Bromides; IndolesOxindoles; Indole/indoline/oxindole; Indoles and derivatives; pharmacetical; Heterocycles series; Halides; Pyrroles & Indoles; Indole; Indoles; Indole Derivatives; Simple Indoles; Pyrroles & Indoles; Halogenated Heterocycles; Heterocyclic Building Blocks; IndolesBuilding Blocks; Heterocycle-Indole series; blocks

Mol File:

52488-36-5.mol

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4-Bromoindole Chemical Properties 

Melting point 

17 °C

Boiling point 

283-285 °C(lit.)

density 

1.563 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.655(lit.)

Fp 

230 °F

storage temp. 

0-6°C

Water Solubility 

Not miscible in water.

Sensitive 

Light Sensitive

BRN 

114891

CAS DataBase Reference

52488-36-5(CAS DataBase Reference)

 

Safety Information 

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36-37/39

WGK Germany 

3

Hazard Note 

Keep Cold/Light Sensitive

HazardClass 

IRRITANT, KEEP COLD

HS Code 

29339990

 

MSDS Information 

 

4-Bromoindole Usage And Synthesis 

Chemical Properties

Clear yellowish-green or dark brown liquid

Uses

A potential inhibitor of GSK-3

Synthesis route

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Reference:

Mei, Tian-Sheng; Wang, Xisheng; Yu, Jin-Quan Journal of the American Chemical Society, 2009 , vol. 131, # 31 p. 10806 – 10807

 

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Reference:

Harrington, Peter J.; Hegedus, Louis S. Journal of Organic Chemistry, 1984 , vol. 49, # 14 p. 2658 – 2662

 

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Reference:

Ruiz, Miriam; Sanchez, J. Domingo; Lopez-Alvarado, Pilar; Menendez, J. Carlos Tetrahedron, 2012 , vol. 68, # 2 p. 705 – 710

 

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Reference:

Somei; Kizu; Kunimoto; Yamada Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 9 p. 3696 – 3708

 

4-Bromoindole Preparation Products And Raw materials 

Preparation Products

Indole-4-boronic   acid-->4-Bromoindole-3-carboxaldehyde

 

Upstream information

4-bromo-1-pivaloylindole; Phosphonium, [(2-bromo-6-nitrophenyl) methyl]triphenyl-, bromide(1:1);2-bromo-6-nitrobenzenediazonium hydrogen sulfate;Formaldehyde;2-(2-Bromo-6-nitrophenyl) ethanol; Bis(pinacolato)diboron; Chlorosulfonyl Isocyanate;Tributyl borate;tert-butoxycarbonyl anhydride; Methyl indole-3-carboxylate;


Downtream information

4-bromo-3-[3-fluoro-4-[[(3-nitropyridin-4-yl)amino]methyl]benzoyl]-N,N-dimethylindole-1-carboxamide; Methyl 2-methyl-1H-indole-4-carboxylate; D-Lysergic acid methyl ester; tert-butyl 4-bromo-3-formylindole-1-carboxylate; 2-(4-bromo-1H-indol-3-yl)ethanol; trifluoroacetic acid; Indole-4-boronic acid, pinacol ester; Indole-4-carboxaldehyde; 4-[4-(1-azabicyclo[2.2.2]octan-3-yloxy)phenyl]-1H-indole; 4-bromo-1-methylindole;


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