Metabolic pathways of amino acids

- May 03, 2018-

The specific ways in which amino acids are involved in metabolism are as follows:

Mainly in the liver: including the following processes: Oxidation of amino: the first step, dehydrogenation, the formation of imipenem;

The generated H2O2 is poisonous and is catalyzed by catalase to produce H2O and O2 and to remove toxicity to the cells.

Non-oxidative denitrification: ① reduction of amino (under strict anaerobic conditions); ② water free amino; ③ dehydration, ④, ⑤ oxidation-reduction, two amino acids react to each other, produce organic acid, ketone acid, ammonia, and ⑥ amide radicals. Amino function. Ammonia transfer is an important way to remove ammonia, in addition to Gly, Lys, Thr, pro, most amino acids can participate in the role of the amino.

α-amino acid and α-ketone acid occur between the amino transfer, the result is the original amino acid to produce the corresponding ketone acid, and the original ketone acid to produce the corresponding amino acids. Joint de-amino: only by the amino function can not eventually take off the amino, the single oxidation of the amino function can not meet the needs of the body de-amino. The organism can remove amino: 1, with glutamate dehydrogenase as the center of the combined de-amino function. The α-amino amino acids are first transferred to Alpha-amyl valerate to produce the corresponding α-keto acid and Glu, and then, by L-glu deaminase, the amino acid is produced and the ammonia is released. 2, through the purine nucleotide cycle of the joint de-amino to do. Skeletal muscle, myocardium, liver and brain are mainly in the form of purine nucleotide circulation.