85838-94-4 N-Boc-1,2,3,6-tetrahydropyridine

85838-94-4 N-Boc-1,2,3,6-tetrahydropyridine

N-BOC-1,2,3,6-TETRAHYDROPYRIDINE Basic information N-BOC-1,2,3,6-TETRAHYDROPYRIDINE Chemical Properties Safety Information MSDS Information N-BOC-1,2,3,6-TETRAHYDROPYRIDINE Usage And Synthesis N-BOC-1,2,3,6-TETRAHYDROPYRIDINE Preparation Products And Raw materials Upstream information...
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Product Details

N-BOC-1,2,3,6-TETRAHYDROPYRIDINE Basic information

Product Name:

N-BOC-1, 2, 3, 6-TETRAHYDROPYRIDINE

Synonyms:

N-TERT-BUTOXYCARBONYL-1, 2, 3, 6-TETRAHYDROPYRIDINE; N-BOC-1, 2, 3, 6-TETRAHYDROPYRIDINE; N-BOC-1, 2, 5, 6-TETRAHYDROPYRIDINE; 1-Boc-1, 2, 3, 6-tetrahydro-pyridine; 1, 2, 3, 6-Tetrahydropyridine, N-BOC protected; 3, 6-Dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester; Tert-butyl5, 6-dihydropyridine-1(2H)-carboxylate; tert-Butyl 3, 6-dihydropyridine-1(2H)-carboxylate

CAS:

85838-94-4

MF:

C10H17NO2

MW:

183.25

EINECS:


Product Categories:

Heterocycle-Pyridine series

Mol File:

85838-94-4.mol

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N-BOC-1,2,3,6-TETRAHYDROPYRIDINE Chemical Properties

Boiling point

78-84℃/5mm

Boiling Point:

241.5ºC at 760 mmHg

Flash Point:

99.9ºC

density

1.029 g/cm3

refractive index

1.4650 to 1.4690

Water Solubility

Insoluble in water. Soluble in organic solvents.


Safety Information

Hazard Codes

Xi,T

Risk Statements

36/37/38-25

Safety Statements

26-36/37/39-45

HazardClass

IRRITANT

Hs code

2933399090


MSDS Information


N-BOC-1,2,3,6-TETRAHYDROPYRIDINE Usage And Synthesis

Chemical Properties

Liquid

Description

tert-Butyl 1, 2, 3, 6-Tetrahydro-1-pyridinecarboxylate is used in the synthesis of antitumor agents. Also used in the synthesis of potent CC chemokine receptor 2 antagonists as antiviral and anticancer therapeutics.

Synthesis   route

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Reference:

Heterocycles, vol. 39, # 1 p. 163 – 170


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Reference:

US2009/163472 A1, ; Page/Page column 27 ; US 20090163472 A1


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Reference:

WO2013/71697 A1, ; Paragraph 00374;


N-BOC-1,2,3,6-TETRAHYDROPYRIDINE Preparation Products   And Raw materials


Upstream information

1-benzylpyridin-1-ium, chloride; 4-Bromotoluene; tert-butyl (3S)-3-methylsulfonyloxypiperidine-1-carboxylate; m-cresol; N-Boc-3-mesyloxypiperidine; tert-butoxycarbonyl anhydride; 4-Hydroxypiperidine; N-Boc-(3-butenyl)(allyl)amine; tert-butyl diallylcarbamate; 1-Benzyl-1, 2, 3, 6-tetrahydropyridine;


Downtream information

1-tert-butyloxycarbonyl-4-(4-methylphenyl)-1, 2, 3, 6-tetrahydropyridine; 4-Fluoropiperidine-N-carboxylic acid tert-butyl ester; N-Boc-1, 2, 3, 6-Tetrahydropyridine;tert-Butyl 7-oxa-3-aza-bicyclo[4. 1. 0]heptane-3-carboxylate; ethene; tert-butyl 4-(4-amino-5-fluoropyrimidin-2-yloxy)piperidine-1-carboxylate; tert-butyl 3-oxo-2, 6-dihydropyridine-1-carboxylate; (RS)-3-(adenin-9-yl)-1-N-tert-butyloxycarbonylpiperidine; (RS)-1-N-tert-butyloxycarbonyl-3-(thymin-1-yl)piperidine; tert-butyl 3-hydroxy-3, 6-dihydro-2H-pyridine-1-carboxylate;


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