71233-25-5 Ethyl N-Boc-3-Oxopiperidine-4-carboxylate

71233-25-5 Ethyl N-Boc-3-Oxopiperidine-4-carboxylate

3-Oxo-Piperidine-1,4-Dicarboxylic Acid 1-Tert-Butyl Ester 4-Ethyl Ester Basic information 3-Oxo-Piperidine-1,4-Dicarboxylic Acid 1-Tert-Butyl Ester 4-Ethyl Ester Chemical Properties Safety Information MSDS Information 3-Oxo-Piperidine-1,4-Dicarboxylic Acid 1-Tert-Butyl Ester 4-Ethyl Ester Usage...
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Product Details

3-Oxo-Piperidine-1,4-Dicarboxylic Acid 1-Tert-Butyl Ester 4-Ethyl Ester Basic information

Product Name:

3-Oxo-Piperidine-1, 4-Dicarboxylic Acid 1-Tert-Butyl Ester 4-Ethyl Ester

Synonyms:

3-Oxo-Piperidine-1, 4-Dicarboxylic Acid 1-Tert-Butyl Ester 4-Ethyl Ester; Ethyl 1-N-Boc-3-oxopiperidine-4-carboxylate; 3-Oxo-piperidine-1-carboxylic acid tert-butyl este; Ethyl N-Boc-3-Oxopiperidine-4-carboxylate; 1-(tert-butoxycarbonyl) -4-ethyl-3-oxopiperidine-4-carboxylic acid; 1-tert-Butyl 4-ethyl   3-oxopiperidine-1, 4-dicarboxylate; 1, 4-Piperidinedicarboxylic acid, 3-oxo-, 1-(1, 1-diMethylethyl) 4-ethyl ester; 1-tert-butyl 4-ethyl 3-hydroxy-5, 6-dihydropyridine-1, 4(2H) -dicarboxylate

CAS:

71233-25-5

MF:

C13H21NO5

MW:

271.31

EINECS:


Product Categories:


Mol File:

71233-25-5.mol

image001_副本.jpg

 

3-Oxo-Piperidine-1,4-Dicarboxylic Acid 1-Tert-Butyl   Ester 4-Ethyl Ester Chemical Properties 

form

Liquid

Density:

1.152 g/cm3

Boiling Point:

364.6ºC at 760 mmHg

Refractive Index:

1.482

 

Safety Information 

Hs code

2933399090

 

MSDS Information 

3-Oxo-Piperidine-1,4-Dicarboxylic Acid 1-Tert-Butyl   Ester 4-Ethyl Ester Usage And Synthesis 

Synthesis route

image003_副本.jpg

Reference:

Toure, B. Barry; Miller-Moslin, Karen;   Yusuff, Naeem; Perez, Lawrence; Dore, Michael; Joud, Carol; Michael, Walter;   Dipietro, Lucian; Van Der Plas, Simon; McEwan, Michael; Lenoir, Francois;   Hoe, Madelene; Karki, Rajesh; Springer, Clayton; Sullivan, John; Levine,   Kymberly; Fiorilla, Catherine; Xie, Xiaoling; Kulathila, Raviraj; Herlihy,   Kara; Porter, Dale; Visser, Michael ACS Medicinal Chemistry Letters, 2013 ,   vol. 4, # 2 p. 186 - 190

 

image005_副本.jpg

1. NOVARTIS AG; MILLER-MOSLIN, Karen; TOURE, Bakary-Barry; VISSER, Michael Scott; YUSUFF,   Naeem Patent: WO2011/29842 A1, 2011 ; Location in patent: Page/Page column 40 ; WO 2011/029842 A1

2. Hao, Bao-Yu; Liu, Jin-Qiang; Zhang, Wei-Han; Chen, Xin-Zhi Synthesis, 2011 , # 8 art. no. F14011SS, p. 1208 – 1212

3. Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 18 p. 4023 – 4028

4. Journal of Medicinal Chemistry, , vol. 49, # 15 p. 4544 – 4567

 

3-Oxo-Piperidine-1,4-Dicarboxylic Acid 1-Tert-Butyl   Ester 4-Ethyl Ester Preparation Products And Raw materials 


Upstream information

tert-butoxycarbonyl anhydride; Ethyl N-Boc-3-Oxopiperidine-4-carboxylate; Ethyl 3-oxopiperidine-4-carboxylate; Ethyl 1-benzyl-3-oxopiperidine-4-carboxylate; Ethyl N-benzyl-3-oxo-4-piperidinecarboxylate hydrochloride;


Downtream information

O1-tert-butyl O4-ethyl 3-(1-phenylethylamino) piperidine-1,4-dicar boxylate; 2-Methyl-2-propanyl 3, 8-diazabicyclo [4.2.0] octane-3-carboxylate; Ethyl N-Boc-3-Oxopiperidine-4-carboxylate; tert-butyl (1R,6S) -4,7-diazabicyclo [4.2.0] octane-7-carboxylate; 3-Boc-3, 8-diazabicyclo[4.2.0] octane; tert-Butyl 4-chloro-5, 6-dihydropyrido[3, 4-d] pyrimidine-7(8H) -carboxylate; tert-butyl 4-amino-3-hydroxypiperidine-1-carboxylate; Boc-isoguvacine;

 

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