1,4-DIHYDRO-4-OXO-QUINOLINE-3-CARBOXYLIC ACID;4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID;AURORA 17733;TIMTEC-BB SBB000272;1,2-Dihydro-4-oxo-quinoline-3-carboxylic acid;1,4-Dihydro-4-oxo-3-quinolinecarboxylic acid;4-Quinolone-3-carboxylic acid;4-Oxo-1,4-dihydroquinoline Carboxylic Acid
4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID Chemical Properties
4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID Usage And Synthesis
4-Oxo-1,4-dihydroquinoline Carboxylic Acid is a novel HIV-1 integrase strand transfer inhibitor.
4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID Preparation Products And Raw materials
SAFETY DATA SHEET
Product name: 1,4-Dihydro-4-oxoquinoline-3-carboxylic Acid
Revision number: 1
2. HAZARDS IDENTIFICATION
Classification of the substance or mixture
PHYSICAL HAZARDS Not classified
Skin corrosion/irritation Category 2
Serious eye damage/eye irritation Category 2A
ENVIRONMENTAL HAZARDS Not classified
Pictograms or hazard symbols
Signal word Warning
Hazard statements Causes skin irritation
Causes serious eye irritation
[Prevention] Wash hands and face thoroughly after handling.
Wear protective gloves, eye protection.
[Response] IF ON SKIN: Wash with plenty of water. If skin irritation occurs: Get medical advice or attention. Take off contaminated clothing and wash it before reuse.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice or attention.
3. COMPOSITION/INFORMATION ON INGREDIENTS
Components: 1,4-Dihydro-4-oxoquinoline-3-carboxylic Acid
CAS RN: 13721-01-2
Chemical Formula: C10H7NO3
4. FIRST AID MEASURES
Inhalation: Remove victim to fresh air and keep at rest in a position comfortable for breathing. Get medical advice/attention if you feel unwell.
Skin contact: Remove/Take off immediately all contaminated clothing. Gently wash with plenty of soap and water. If skin irritation or rash occurs: Get medical advice/attention.
Eye contact: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
Ingestion: Get medical advice/attention if you feel unwell. Rinse mouth.
Protection of first-aiders: A rescuer should wear personal protective equipment, such as rubber gloves and air-tight goggles.
5. FIRE-FIGHTING MEASURES
Suitable extinguishing media: Dry chemical, foam, water spray, carbon dioxide.
Specific hazards arising from the chemical: Take care as it may decompose upon combustion or in high temperatures to generate poisonous fume.
Precautions for firefighters: Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place. In case of fire in the surroundings: Remove movable containers if safe to do so.
Special protective equipment for firefighters: When extinguishing fire, be sure to wear personal protective equipment
6. ACCIDENTAL RELEASE MEASURES
Personal precautions, protective equipment and emergency procedures: Use personal protective equipment. Keep people away from and upwind of spill/leak. Entry to non-involved personnel should be controlled around the leakage area by roping off, etc.
Environmental precautions: Prevent product from entering drains.
Methods and materials for containment and cleaning up: Sweep dust to collect it into an airtight container, taking care not to disperse it. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.
7. HANDLING AND STORAGE
Precautions for safe handling Technical measures: Handling is performed in a well ventilated place. Wear suitable protective equipment. Prevent dispersion of dust. Wash hands and face thoroughly after handling. Use a local exhaust if dust or aerosol will be generated.
Advice on safe handling: Avoid contact with skin, eyes and clothing.
Conditions for safe storage, including any incompatibilities
Storage conditions: Keep container tightly closed. Store in a cool and dark place. Store away from incompatible materials such as oxidizing agents.
Packaging material: Comply with laws.
8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Engineering controls: Install a closed system or local exhaust as possible so that workers should not be exposed directly. Also install safety shower and eye bath.
Personal protective equipment Respiratory protection: Dust respirator. Follow local and national regulations.
Hand protection: Protective gloves.
Eye protection: Safety glasses. A face-shield, if the situation requires.
Skin and body protection: Protective clothing. Protective boots, if the situation requires.
9. PHYSICAL AND CHEMICAL PROPERTIES
Physical state (20°C): Solid
Form: Crystal - Powder
Colour: White - Slightly pale yellow
Odour: No data available
pH: No data available
Melting point/freezing point: 265°C (dec.)
Boiling point/range: No data available
Flash point: No data available
Flammability or explosive limits:
Lower: No data available
Upper: No data available
Relative density: No data available
[Water] No data available
Soluble: Hot dimethylformamide(DMF)
10. STABILITY AND REACTIVITY
Chemical stability: Stable under proper conditions.
Possibility of hazardous reactions: No special reactivity has been reported.
Incompatible materials: Oxidizing agents
Hazardous decomposition products: Carbon dioxide, Carbon monoxide, Nitrogen oxides (NOx)
11. TOXICOLOGICAL INFORMATION
Acute Toxicity: No data available
Skin corrosion/irritation: No data available
Serious eye damage/irritation: No data available
Germ cell mutagenicity: No data available
Carcinogenicity: IARC = No data available
NTP = No data available
Reproductive toxicity: No data available
12. ECOLOGICAL INFORMATION
Fish: No data available
Crustacea: No data available
Algae: No data available
Persistence / degradability: No data available
Bioaccumulative potential(BCF): No data available
Mobility in soil Log Pow: No data available
Soil adsorption (Koc): No data available
Henry's Law (PaM 3/mol): No data available
13. DISPOSAL CONSIDERATIONS
Recycle to process, if possible. Consult your local regional authorities. You may be able to dissolve or mix material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system.
Observe all federal, state and local regulations when disposing of the substance.
14. TRANSPORT INFORMATION
Hazards Class: Does not correspond to the classification standard of the United Nations
UN-No: Not listed
15. REGULATORY INFORMATION
Regulations on the Control over Safety of Dangerous Chemicals (State Council announces on January 26, 2002 and revised on February 16,2011): Safe use and production, the storage of a dangerous chemical, transport, loading and unloading were prescribed.