4-Amino-2-(trifluoromethyl)benzonitrile Basic information
Product Name: | 4-Amino-2- (trifluoromethyl) benzonitrile |
Synonyms: | BUTTPARK 22\01-63; 2-CYANO-5-AMINOBENZOTRIFLUORIDE; 5-AMINO-2-CYANOBENZOTRIFLUORIDE; 4-CYANO-3-TRIFLUOROMETHYLANILINE; 4-AMINO-2-TRIFLUOROMETHYLBENZONITRILE; 5-AMINO-2-CYANO BENZOTRIFLUORID; 4-Amino-2- (trifluoromethyl) benzontrile; 4-Bromo-2-TrifluoromethylAniline/4-Bromo-2- (Trifluoromethyl) Aniline/2-Amino-5-Bromobenzotrifluoride |
CAS: | 654-70-6 |
MF: | C8H5F3N2 |
MW: | 186.13 |
EINECS: | -0 |
Product Categories: | Trifluoromethylbenzene serise; Chemical intermediate for Bicalutamide; Aromatic Nitriles;Aromatic Halides (substituted); Phenyls & Phenyl-Het; Aniline; Bicalutamide; Chemical Amines; Benzonitriles (Building Blocks for Liquid Crystals); Building Blocks for Liquid Crystals; Functional Materials; Benzotrifluoride Series; Amines; Aromatics; Phenyls & Phenyl-Het; Intermediates; Building Blocks; C8 to C9; Chemical Synthesis; Cyanides/Nitriles; Nitrogen Compounds; Organic Building Blocks |
Mol File: | 654-70-6.mol |
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4-Amino-2-(trifluoromethyl)benzonitrile Chemical Properties
Melting point | 141-145 °C(lit.) |
storage temp. | Room temperature. |
form | Powder |
color | White to off-white |
BRN | 3278074 |
CAS DataBase Reference | 654-70-6(CAS DataBase Reference) |
NIST Chemistry Reference | 5-Amino-2-cyanobenzotrifluoride(654-70-6) |
Safety Information
Hazard Codes | Xn,T |
Risk Statements | 22-43-36/37/38-20/21/22 |
Safety Statements | 36-45-37/39-26 |
RIDADR | 3439 |
WGK Germany | 3 |
Hazard Note | Toxic |
HazardClass | 6.1 |
PackingGroup | III |
MSDS Information
4-Amino-2-(trifluoromethyl)benzonitrile Usage And Synthesis
Chemical Properties | Off-White Solid |
Uses | Used for the preparation of benzene derivatives as non-steroidal androgen receptor modulators. |
Intermediate as | 841205-47-8 ENOBOSAM(MK2866), 90357-06-5 Bicalutamide, 956104-40-8 Apalutamide and 915087-33-1 Enzalutamide |
4-Amino-2-(trifluoromethyl)benzonitrile Preparation Products And Raw materials
Upstream information
2-oxopropanoyl chloride; 3-Aminobenzotrifluoride; Methacryloyl chloride; Copper(I) cyanide; N-[3-(trifluoromethyl) phenyl]acetamide; 3-(4-fluorophenyl) sulfanyl-2-hydroxy-2-methylpropanoic acid; phosgene; 5-chlorosalicylic acid; (2R) -3-Bromo-2-hydroxy-2-methylpropionic acid; Acetic anhydride;
Downtream information
4-amino-5-iodo-2-(trifluoromethyl) benzonitrile; N-[4-Cyano-3-(Trifluoromethyl) Phenyl]-2-Methacrylamide; 4-(2, 2, 2-trifluoroethylamino) -2- (trifluoromethyl) benzonitrile; N- [4-Cyano-3-(trifluoromethyl) phenyl]methacrylamide epoxide; 4-[3-(4-hydroxybutyl) -4, 4-dimethyl-2, 5-dioxoimidazolidin-1-yl] -2-(trifluoromethyl) benzonitrile; 4-[(4-Ethyl-1-piperazinyl) methyl] -3-(trifluoromethyl) aniline; N-[4-cyano-3- (trifluoromethyl) phenyl]-2, 2, 2-trifluoro-acetamide; N-[4-Cyano-3-(trifluoromethyl) phenyl] -2-oxopropanamide; 4-(4, 4-dimethyl-2, 5-dioxoimidazolidin-1-yl)-2-(trifluoromethyl) benzonitrile; 5-chloro-N- [4-cyano-3-(trifluoromethyl) phenyl] -2-hydroxybenzamide;
